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EUBCE 2026 - Marta FRANCO DE BENITO - Computational Approaches to Support Protein Fish By-Products Valorisation to Produce Bioactive Peptides

Computational Approaches to Support Protein Fish By-Products Valorisation to Produce Bioactive Peptides

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Resource efficient bioeconomy

Resource efficient biomass use assessment approaches

Computational Approaches to Support Protein Fish By-Products Valorisation to Produce Bioactive Peptides

Short Introductive summary

Within the VALORISH project, IDENER developed a computational framework to valorise protein-rich by-products from the fishing industry by identifying bacteria capable of converting fish-derived proteins into bioactive peptides. This in silico protocol integrates enzymatic digestion simulations, genome-scale metabolic modelling, and bioactivity inference to predict both the proteolytic efficiency and functional potential of microbial strains. Applied to 81 EFSA-approved bacteria and eight protein substrates from shrimp, hake, and cod, the workflow enabled the selection of 17 promising strains for experimental validation. This approach illustrates how computational biology can accelerate the design of sustainable bioprocesses for transforming fish waste into high-value bioactive compounds, contributing to circular and zero-waste bioeconomy goals.

Presenter

Moderator portrait

Marta FRANCO DE BENITO

Idener Research and Development A.I.E., Biotechnology, SPAIN

Presenter's biography

Project Coordinator and Senior Researcher at IDENER.ai, specialized in bioinformatics and computational biology. I hold a Master’s degree in Bioinformatics and am currently pursuing an Industrial PhD in collaboration with the University of Burgos, focused on applied computational approaches.

Biographies and Short introductive summaries are supplied directly by presenters and are published here unedited


Co-authors:

M. Cebrián, Idener.ai, La Rinconada, SPAIN
M. Franco, Idener.ai, La Rinconada, SPAIN
A. Mishra, Idener.ai, La Rinconada, SPAIN
I. de las Heras, Idener.ai, La Rinconada, SPAIN

Session reference: 3CO.9.4